Chelsea Handler on How to Make Drastic Changes, Accept Your Mistakes, and What Turning 50 Means to Her!

Chelsea Handler (comedian, television host, bestselling author) opens up about her transformative journey, from her powerful lessons on sisterhood learned from a tense meeting with Jane Fonda to the moment she realized her tough exterior was holding her back. Mayim breaks down her latest book, “I’ll Have What She’s Having” and Chelsea’s dating history, including her break-up with Jo Koy. Chelsea reveals how confronting deep-rooted anger fueled by childhood grief led her to therapy and spirituality, giving her the strength to evolve and embrace new forms of healing. Plus, she shares how turning 50 has reshaped her perspective on life, relationships, and finding freedom in saying "no"—a life-changing shift that’s led her to enjoy the freedom of not having kids while still embracing the joys of being a "stepmom" to many.