Tizanidine Pharmacology
Real Life Pharmacology - Pharmacology Education for Health Care Professionals - Un pódcast de Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist - Jueves
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Tizanidine is primarily broken down by CYP1A2. Ciprofloxacin can inhibit CYP1A2 and cause higher tizanidine concentrations. Tizanidine has a similar classification as clonidine. Pay attention to adverse effects like hypotension and bradycardia. When patients taking routine tizanidine stop taking it, there is potential for a discontinuation syndrome that may lead to rebound hypertension. Dry mouth and CNS depression are common adverse effects of tizanidine.
